Senior Clinical Scientist

Iovance Biotherapeutics aims to be the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) therapy for people with cancer. We are pioneering a transformational approach by harnessing the human immune system to recognize and attack diverse cancer cells in each patient.

The Iovance TIL platform has demonstrated promising clinical data across multiple solid tumors. We are committed to continuous innovation in cell therapy, including gene-edited therapies.

Overview

The Senior Clinical Scientist supports the development and execution of Clinical Development Plans (CDPs) and works closely with Medical Directors and Clinical Science Physicians to ensure effective clinical program delivery.

This role includes clinical documentation, cross-functional collaboration, training of study personnel, and external engagement with key stakeholders such as KOLs, vendors, and research groups.

Key Responsibilities

• Support design and writing of clinical protocols and study documents (ICFs, charters, manuals).
• Serve as subject matter expert on study design and trial procedures.
• Develop training materials for investigational sites.
• Act as a point of contact for protocol-related questions.
• Support medical monitoring and CRO oversight activities.
• Analyze and review clinical data for trends and insights.
• Contribute to regulatory documents (INDs, Investigator Brochures, Clinical Study Reports).
• Support clinical development planning and innovative trial design evaluation.
• Monitor scientific, clinical, and regulatory developments.

Qualifications

• MD, PhD, or PharmD with oncology experience required.
• Cell therapy experience preferred.
• 6+ years in clinical research; 3–5 years in clinical science/development preferred.
• Strong knowledge of GCP/ICH and clinical trial processes.
• Experience in data analysis, interpretation, and trend identification.
• Familiarity with tools like Spotfire or similar.
• Knowledge of oncology therapies (e.g., NSCLC) preferred.
• Experience with CROs, Phase I–III trials, and global studies preferred.
• Strong analytical, project management, and communication skills.
• Ability to manage multiple priorities and meet deadlines.
• Willingness to travel (~10%).

Physical Requirements

• Ability to sit or stand for extended periods.
• Light physical activity such as lifting small objects.
• Strong visual and computer-based work capability.
• Repetitive hand and wrist movements.
• Clear communication ability.

Work Environment

This role operates in a professional workplace or remote office environment. Remote employees must maintain a safe and suitable workspace.

Salary

$150,000 – $185,000 USD annually

Equal Opportunity

Iovance is an equal-opportunity employer committed to diversity and inclusion. All applicants will be considered regardless of protected characteristics.

For accommodations, contact: careers@iovance.com